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−  ''' Gravitation as binding force between Molecules to explain Brownian Motion in Multi Molecule Theory using Dynamic Universe Model
 
   
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−  Nanobiotechnology is a wonderful multidisciplinary budding science have its roots in four main branches of science viz, Particle Physics, Nano Biology, and Micro chemistry and Engineering. This is Nano particle Physics portion which is forming the basis of the Nanobiotechnology. Until today the behaviour of fluid particles in Brownian motion are explained using Single molecule theory. But many questions remain for the last 300 years or so, how this Brownian motion happens? Why collisions happen between the Molecules? How the momentum is generated in the starting place? What are the are the trajectories of individual particles or molecules? The Physics and the calculations behind the force and individual velocities of molecules with relevant theoretical analysis is proposed in this paper. For the Multi Molecule Theory (MMT) Subbarao Simulations (SSMMT) were developed in the last two months. Here we will discuss the basic theory, Excel implementation, simulation results of using, and four the attached Excel files which confirmed the proposition that the Gravitation is the binding force between molecules on different cases. Earlier the concepts of this paper were published as five separate papers, here we present the whole work as a single paper so that referencing will be easy. Vak 18092020 Bhilai
 
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−  === Introduction: Brownian motion ===
 
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−  Brownian motion is well known. This can be seen in Liquids, gases easily and can be seen in solids with high end electron microscopes. For example, lets observe a single colloid with an optical microscope. Observe a 2 μm latex particle, which will undergo a constant motion in water within seconds of placing it in water in all the three dimensions. This random motion is called Brownian Motion. The sizes of the particles have a key role to play, the same type of motion is observed for colloids of 1 nm in diameter as well. This length corresponds to the size of single molecules, biomolecules such as DNA, RNA, proteins. They should therefore experience this type of motions. See very good explanations in the paper ‘Life at low Reynolds number’ by Purcell [1]. Here in this paper we will try to develop some equations for molecular forces, Brownian motions, coefficient of diffusion etc., using this Multi Molecule Theory instead of the age old ‘single Molecule theory’.
 
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−  Nanobiotechnology is a new budding branch of science. Here in this section of Sklogwiki we try to attempt the explanation of Brownian Motion using the concepts of Dynamic Universe Model. We will try to modify SITA simulation software for using in this platform and call it as Subbarao Simulations. In section 4.1 the formation of excelsheet was shown. And we will discuss salient formation points for of final Results. We did not assume any boundaries for molecules or nanoparticle movements.
 
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−  === Introduction to Our work: ===
 
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−  We did 1500 iterations for two different types data files in these simulations as we discussed with same the staring data. In the second type earth gravity was also considered along with the gravity between individual molecules and we did 7000 iterations. In a third test we transferred all the data into another old Laptop and conducted 2015 iterations just to confirm the data and results with earth gravity.
 
−  For each simulation test of 500 iterations, the calculation time taken is approx. 4 to 5 hours.
 
−  In the three cases Viscosity of the (muddy) water plus all the additives is increased from 1 to 4 times higher. that means intermolecular distances were reduced to 25% of original distances. Other two types are considered further at present.
 
−  We took a microsecond time step between iterations. Though this is 1000 times high observed movements of molecules (which are of about 10 nano seconds), we considered this to reduce the number of iterations to view faster results.
 
−  When we considered earth gravitation, we got better displacements.
 
−  Section 5.2.1. gives details about various Excel file attachments with this paper. Further details can be obtained the author.
 
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−  === '''Advantages of this Method SSMMT''' ===
 
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−  Dynamic Universe Model entered the new era and new subject of NANOBIOTECHNOLOGY, which is a budding science and is a conglomeration of four main branches of science viz, Physics, Biology, and chemistry and Engineering. This branch of science is very powerful and versatile. In these simulations 133 particles were considered. Higher number gives higher accuracies in simulations. Each set of 500 iterations simulation took an average of 5 hours of continuous calculations on this Laptop.
 
−  A humble attempt is made to develop mathematical background for the Subbarao Simulation of Multi Molecule theory (SSMMT) for an oral presentation in the conference Nanobiotech 2020.
 
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−  Another important factor to be noted is gravitation is a weak force, but the gravitation action of Multiple molecules and number of iterations gave enough movement to cause the Brownian motions in fluids, which is evident from the attached graphs. I could not do any simulation for more than 7000 iterations because my laptop was getting heated up and I felt they are sufficient to safely conclude that Gravitation is the binding force between the molecules in water. Though it is weak force, but the nano movements of molecules of the order of 1020 nano meters in every nano second are added together with multiple innumerable number of molecules acting gravitationally increases these movements heavily.
 
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−  Assembly of molecules in test tubes usually hinder the behaviors of single molecules. The ensemble averages out the behavior of single molecules. Now with the help of this SSMMT we don’t have to do elaborate methods to Isolate single molecule, to do variety of EXPERIMENTS with SIMPLER and CHEAPER LAB equipment. Simple experimental Fluctuations NEED NOT be screened out. As usual the observation of molecular events can be done with single molecule theories.
 
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−  Mathematics for ‘single molecule’ theories were fully developed. There are many for problems and difficulties for isolating single molecule for observations via an optical micro scope. With SSMMT such problems will be reduced.
 
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−  All these simulations and papers were done in just one month of time. More iterations are required to the tune of millions to see displacements to see fully. Here with sets of simulations we can safely conclude that Gravitation is the binding attraction force. Maybe I will do bigger simulation on a bigger computer if I can get some resources.
 
−  A humble attempt is made to develop mathematical background for the Subbarao Simulation of Multi Molecule theory for an oral presentation in the conference Nanobiotech 2020. And thus a problem of more than 300 years old is getting a solution.
 
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−  === History: ===
 
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−  In 1959, Alder and Wainwright[4] used an IBM 704 computer to simulate perfectly elastic collisions between hard spheres. They said “ this manybody problem” was solved numerically using simultaneous equations of motion. Numerical methods give raise to errors always. This method solves many problems in both equilibrium and nonequilibrium statistical mechanics [5]. Probably the first simulation of matter, Gibson et al. simulated radiation damage of solid copper by using a Born–Mayer type of repulsive interaction along with a cohesive surface force. In his paper “ Correlations in the Motion of Atoms in Liquid Argon” in 1964, Rehman A., said “The paircorrelation function and the constant of selfdiffusion are found to agree well with experiment; the latter is 15% lower than the experimental value. The spectrum of the velocity autocorrelation function shows a broad maximum in the frequency region ω=0.25(kBT/ℏ)”. He used a system of 864 particles interacting with a LennardJones potential and obeying classical equations of motion [6]. These are some of the Nbody problem type solutions about 60 years back.
 
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−  === Mathematical Background for Multi Molecule Theory of Nanobiotechnology ===
 
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−  Let us assume an inhomogeneous set of N Molecules as a Colloid. This colloid is mix of water molecules, Individual proteins, polymers of living matter such as DNA, RNA, actin or microtubules, molecular motors etc. Water is universal solvent, universally available, so we take water + colloid particles for this theory. These don’t react with each other chemically. All these molecules behave like bouncing rubber balls, sizes are different All these set will have different masses in accordance with their type. This colloid will lead to have Brownian motions of the NanoBioParticles due to mutual gravitation attraction forces between individual particles. We will consider the gravitation influence of Earth, Sun, Moon etc., also on this colloid. Lets take total number of molecules to be 133, to use modified SITA calculations. We call these calculations as SUBBARAO Simulations or Multi Molecule Theory (Later we will call as ‘SSMMT’). For a broader perspective, let us call this set of all the systems of point masses as an Ensemble. Let us further assume that there are many Ensembles each consisting of a different number of systems with different number of point masses. Similarly, let us further call a group of Ensembles as Aggregate. Let us further define a Conglomeration as a set of Aggregates and let a further higher system have a number of conglomerations and so on and so forth.
 
−  We will start with133 particles / molecules in a Microcubical cubical in a glass beaker. We will assume a MicroCubicle in this beaker with invisible elastic walls. We will use 3D Cartesian coordinates with some appropriate center of its axes in this beaker.
 
−   All the boundaries are perfectly elastic. Any NanobioParticle which hits the boundary will return according to Newtons laws. We will take nano distances and picosecond times as appropriate. To this case. We assume all the molecules to be perfect elastic spheres. There will be bumping and collisions between particles, and each pair will move and trace their path back after the elastic collision between the two. We can detect collisions by SSMMT software by two bumping particles when the center to center distance is less than or equal to the sum of two molecular radii of these Biospheres.
 
−  So it is obvious that the distance between the two molecules will increase and their velocities reverses after each pair’s collision.
 
−  In this paper we will not consider gravitational repulsion at very low distances, only the bumping will happen at that distance, later we will introduce this concept in a next paper….
 
−  Similarly, we will introduce the Viscosity forces in another forthcoming paper.
 
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−  Initially, let us assume a set of N mutually gravitating point masses in a system under Newtonian Gravitation. All these Nanobioparticles will have some finite radii ri which we will use for the calculation of bumping or collision in the SSMMT software.
 
−  Let the <math> \alpha </math> th point mass has mass <math> m_\alpha </math> , and is in position <math> x_\alpha </math>. In addition to the mutual gravitational force, there exists an external <math> \phi_{ext} </math> , due to other systems, ensembles, aggregates, and conglomerations etc., which also influence the total force <math> F_ \alpha </math> acting on the point mass <math> \alpha </math>. In this case, the <math> \phi_{ext} </math> is not a constant universal Gravitational field but it is the total vectorial sum of fields at <math> x_\alpha </math> due to all the external to its system bodies and with that configuration at that moment of time, external to its system of N point masses.Total Mass of system
 
−  = <math>M = \sum_{\alpha=1}^N m_\alpha </math> (1)
 
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−  As it is very difficult for me to type all the equations here , I will just jump to the final equation, Any person wanted to see all the equations can get a copy of full set by email from me.
 
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−  '''Total AGGREGATE Equations :( Aggregate consists of many Ensembles and systems)'''
 
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−  Assuming these forces are conservative, we can find the resultant force
 
−  <math>F_{ext}(\alpha) = \sum_{\beta=1 \ \alpha\ne\beta}^{N^\gamma}\frac{G{m_ \beta^\gamma}}{\left \vert x^{\gamma \beta}x^{\gamma \alpha} \right \vert} \sum_{\beta=1 \ \alpha\ne\beta}^{N^ {\delta\gamma}}\frac{G{m_ \beta^ {\delta\gamma}}}{\left \vert x^{\delta \gamma \beta}x^{\delta \gamma \alpha} \right \vert}</math> (2)
 
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−  The Equation 2 is the main powerful equation, which gives many results that are not possible otherwise today. This tensor can be subdivided into 21000 small equations without any differential equations or integral equations. Hence, this set up gives a unique solution of Cartesian X, Y, Z components of coordinates, velocities and accelerations of each point mass in the setup for that particular instant of time.
 
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−  === Dynamic Universe Model ===
 
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−  A point to be noted here is that the Dynamic Universe Model never reduces to General relativity on any condition. It uses a different type of mathematics based on Newtonian physics. This mathematics used here is simple and straightforward. As there are no differential equations present in Dynamic Universe Model, the set of equations give single solution in x y z Cartesian coordinates for every point mass for every time step. All the mathematics and the Excel based software details are explained in the three books published by the author[14, 15, 16] In the first book, the solution to Nbody problemcalled Dynamic Universe Model (SITA) is presented; which is singularityfree, interbody collision free and dynamically stable. The Basic Theory of Dynamic Universe Model published in 2010 [14]. The second book in the series describes the SITA software in EXCEL emphasizing the singularity free portions. This book written in 2011 [15] explains more than 21,000 different equations. The third book describes the SITA software in EXCEL in the accompanying CD / DVD emphasizing mainly HANDS ON usage of a simplified version in an easy way. The third book is a simplified version and contains explanation for 3000 equations instead of earlier 21000 and this book also was written in 2011[16]. Some of the other papers published by the author are available at refs. [17, 19].
 
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−  SITA solution can be used in many places like presently unsolved applications like Pioneer anomaly at the Solar system level, Missing mass due to Star circular velocities and Galaxy disk formation at Galaxy level etc. Here we are using it for prediction of blue shifted Galaxies.
 
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−  === Further Details ===
 
−  For discussions and details please contact the Author at his mail Id <snp.gupta@gmail.com> or see the web page.... https://vaksdynamicuniversemodel.blogspot.com/
 
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−  === Acknowledgements ===
 
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−  I thank Maa Vak for giving me continuous Guidance on this new work. I also thank Prof Caroline Kelly, Program Director, Nanobiotech 2020, for asking me to deliver a lecture on NANOBIOTECHNOLOGY, which is a perfectly new subject for me. And she inspired me to do this work for the upcoming online Conference during Aug 34, 2020.
 