Time step

The time-step is an important variable in molecular dynamics simulations. It is usually of the order of femto (Failed to parse (SVG (MathML can be enabled via browser plugin): Invalid response ("Math extension cannot connect to Restbase.") from server "https://wikimedia.org/api/rest_v1/":): {\displaystyle 10^{-15}} ) seconds.

Multiple time steps

A well known multiple time step method is the reversible reference system propagator algorithm (RESPA):

• M. Tuckerman, B. J. Berne and G. J. Martyna "Reversible multiple time scale molecular dynamics", Journal of Chemical Physics 97 pp. 1990-2001 (1992)